Nitric oxide is chemical compound that plays a major role in male sexual function. An abundance of nitric oxide can improve circulation and lead to more frequent erections, and conversely, a low supply of nitric oxide can lead to premature ejaculation. Nitric oxide is so effective that some popular prescription medications rely solely on this one chemical's mechanism of action to treat erectile dysfunction (ED).
Nitric oxide's mechanism of action is very simple. The inner-lining of blood vessels use nitric oxide to signal the surrounding smooth muscle to relax. This leads to vasodilation (blood vessel dilation), and therefore increased blood flow. Increased blood flow can lead to more frequent erections- it's that simple. Some popular prescription ED medications work by preventing a key enzyme (known as phosphodiesterase type 5, or "PDE5") from destroying nitric oxide, resulting in higher nitric oxide levels. These medicines are commonly referred to as PDE-5 inhibitors.
Recently, PDE-5 inhibitors have also been found to play a role in premature ejaculation . This is believed to be due to secondary effects- aside from the primary effect of increasing nitric oxide. Following a study conducted at the Mansoura Faculty of Medicine, researchers stated that some possible causes for prolonging ejaculation are that PDE-5 inhibitors modulate the contractile response of the vas deferens, seminal vesicles, prostate, and urethra .
There are two ways to increase nitric oxide levels in the human body. The first method is to introduce a substance that the body uses to produce nitric oxide, such as Arginine. Arginine is a non-essential amino acid. In other words the human body is capable of producing sufficient amount of Arginine on its own, without supplementation. However, when Arginine is ingested, nitric oxide is synthesized from Arginine by the enzyme NO synthase (NOS)
You can cure your erectile dysfunction at home, using safe, well-tried and trusted techniques. Most doctors would like to see a combination of treatment approaches - lifestyle changes such as stopping smoking, losing the excess pounds, and increasing one's level of physical activity may be enough for a man to get his erection back and cure disfunzione erettile.
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